ESI Team
Group leader
Contact:
hartmut.schlichting@tum.de
Postdoc
visiting researcher / consultant
Scientist / computer science
Former members
Karolina Stoiber
Master Theses – Bachelor Theses – Working Students
The ESI team welcomes students to join as working students or for master / bachelor thesis with background or interest in:
- instrumentation and chemistry of mass spectrometry
- development of analytical instrumentation compounds (electronics, UHV/mechanics, software),
- surface science, simulations and (bio)chemistry
- scanning probe techniques
- DIY’er
Current scope of work:
- Development, optimization and test of innovative deposition methods (work on hardware like ion source and guides, pressure stages, quadrupole, electronics)
- Expansion of the spectrum of species successfully deposited (in particular towards higher masses e.g. protein complexes, nano-/virus(like) particles; and objects at the electronics/biomolecule interface)
- Optimization of sample preparation principles and their impact on ionization efficiency
Potential projects may cover:
- Building blocks: analysis of DNA and protein mono/oligomers on coinage surfaces (in continuation of results from an ongoing PhD project), deposition in layers (sandwich),
- Electrospray process: implementation of sheaths gas, assessment of emitter geometries and materials in context with ionization efficiency,
- Electrolyte physics and chemistry of droplet building and ionization, use of additives (charge enhancers, solubilizers),
- Soft/reactive landing: assessment of different energy schemes applied to molecules prone to oligomerization, to decomposition or those carrying core units with varying functional groups – effects on surfaces
- Quadrupole and overall performance optimization with respect to transmission, resolution, recovery and calibration