Elisabeth's paper just went online: Falgenhauer, E., von Schönberg, S., Meng, C., Mückl, A., Vogele, K., Emslander, Q., Ludwig, C. and Simmel, F..C. (2021), Evaluation of an E. coli cell extract prepared by lysozyme-assisted sonication via gene expression, phage assembly and... [more]

Successful PhD Defenses in 2021: Marisa Götzfried (22.01.) Andrea Meyer (29.01.) [more]

Successful PhD defenses in 2020: Kilian Vogele (15.09.) Ali Aghebat Rafat (13.11.) Daniela Ziegler (17.12.) [more]

Publication: Henningsen, J., Schwarz-Schilling, M., Leibl, A., Gutiérrez, J. N., Sagredo, S., & Simmel, F. C. (2020). Single Cell Characterization of a Synthetic Bacterial Clock with a Hybrid Feedback Loop Containing dCas9-sgRNA. ACS Synthetic Biology, 9(12), 3377–3387 ... [more]

Publication: Frank, T., Vogele, K., Dupin, A., Simmel, F. C., & Pirzer, T. (2020). Growth of Giant Peptide Vesicles Driven by Compartmentalized Transcription-Translation Activity. Chemistry Eur. J., 26(72), 17356–17360. [more]

Successful PhD defenses in 2019: Martin Langecker (22.03.) Enzo Kopperger (24.05.) Matthaeus Schwarz-Schilling (16.07.) Aurore Dupin (31.10.) [more]

Publication: M. A. Goetzfried, K. Vogele, A. Mückl, M. Kaiser, N. B. Holland, F. C. Simmel, T. Pirzer, Periodic Operation of a Dynamic DNA Origami Structure Utilizing the Hydrophilic–Hydrophobic Phase-Transition of Stimulus-Sensitive Polypeptides, Small, 1903541 (2019). ... [more]

 F. C. Simmel, B. Yurke, H. Singh: Principles and applications of nucleic acid strand displacement reactions, Chemical Reviews, Article ASAP(2019). DOI: 10.1021/acs.chemrev.8b00580 (2019) [more]

Using water-in-oil droplets, we have created two-dimensional networks of artificial cells separated by lipid bilayer interfaces. Within this "micro-tissue" the cells can communicate via the exchange of small molecule signals. Coupling these signals to cell-free genetic feedback... [more]

K. Vogele, J. List, F. C. Simmel, T. Pirzer Langmuir (2018). This article is part of the Nucleic Acids Nanoscience at Interfaces special issue. DOI: 10.1021/acs.langmuir.8b01770 [more]

L. Aufinger, F. C. Simmel Angew. Chem. Int. Ed. 57, published online (2018) DOI: 10.1002/anie.201809374 [more]

In a Chinese-German collaboration with Chunhai Fan, Huajie Liu and coworkers, localized DNA strand displacement cascades were realized that allow exploration of paths in tree-like graphs defined on the origami platforms. Read the full story here: J. Chao, J. Wang, F. Wang, X.... [more]

This years iGEM team Munich, hosted by the Simmel lab, wins multiple trophies in the overgraduate section at the iGEM giant jamboree: "Best Manufacturing Project", "Best Presentation", "Best Wiki", "Best Software Tool", "Best Entrepreneurship" and last but not least 1st Runner Up... [more]

G. Pardatscher*, M. Schwarz-Schilling*, S. Sagredo, F. C. SimmelJ. Vis. Exp. (140), e58634, (2018)DOI: 10.3791/58634 [more]

K. Vogele, T. Frank, L. Gasser, M. A. Goetzfried, M. W. Hackl, S. A. Sieber, F. C. Simmel, and Tobias PirzerNature Communications 9, 3862:1–7 (2018)DOI: 10.1038/s41467-018-06379-8 [more]

A. Mückl*, M. Schwarz-Schilling*, K. Fischer, and F. C. SimmelPLOS ONE, 13(9): e0198058 (2018)DOI: 10.1371/journal.pone.0198058 [more]

The international Genetically Engineered Machine (iGEM) Competition is the biggest synthetic biology student competition in the world with over 300 teams from 44 countries. Following last year's success, the Simmel lab is again supervising a team of highly motivated students who... [more]

M. Schwarz-Schilling, A. Dupin, F. Chizzolini, S. Krishnan, S. S. Mansy, and F. C. SimmelNano Letters 18, 2650–2657 (2018)DOI: 10.1021/acs.nanolett.8b00526 [more]

Perspective article by Björn Högberg: Remote control of nanoscale devices Cover of Science Vol 359, Issue 6373: Animated video: [more]

After developing their interdisciplinary diagnostics project over the summer in the laboratory of Prof. Dr. Friedrich Simmel, the Munich team (TUM and LMU) was awarded the 1st Runner Up Prize of the "Overgraduate" section. Furthermore, it received special awards in the categories... [more]

Cover of Nature Nanotechnology (December 2016). Link Image of the month by 'Wired UK' (02/17) Ten years in images (Nature Nanotechnology anniversary feature). DOI: 10.1038/nnano.2016.190 Image of the month by 'Spektrum der Wissenschaft' (October 2016). Link Images of the month... [more]

K. Vogele, J. List, G. Pardatscher, N. B. Holland, F. C. Simmel, and T. Pirzer DOI: 10.1021/acsnano.6b06635 [more] [more]

Swati Krishnan, Daniela Ziegler, Vera Arnaut, Thomas G. Martin, Korbinian Kapsner, Katharina Henneberg, Andreas R. Bausch, Hendrik Dietz & Friedrich C. Simmel DOI:10.1038/ncomms12787 [more]

“The DNA Computing Scientist 2016” goes to Friedrich Simmel for his contributions in advancing DNA based networks and self-organization of DNA-based systems. [more]

Aradhana Chopra, Swati Krishnan, and Friedrich C. Simmel DOI: 10.1021/acs.nanolett.6b03586 [more]

Normally, individual molecules of genetic material repel each other. However, when space is limited DNA molecules must be packed together more tightly. This case arises in sperm, cell nuclei and the protein shells of viruses. An international team of physicists has now succeeded... [more]