Precise monitoring of the lung

X-rays and fluorescence imaging of the lungs of a mouse enable tracking of drug delivery

Scientists at the Helmholtz Zentrum München and the Munich School of BioEngineering (MSB) at the Technical University of Munich (TUM) have presented a combination of imaging techniques that allow real-time monitoring of the delivery of inhaled drugs within the lungs of mice and their absorption in the lung tissue. The results are intended to guide the development of high-efficacy drugs with fewer side effects for treating human lung diseases. The Munich Compact Light Source (MuCLS), a unique, compact particle accelerator that generates high-brilliance X-rays, was used to make the measurements at the MSB. The researchers reported their results in the journal SMALL.

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